Glixx Laboratories Inc
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Glixx Laboratorie
CAS: N/A
Chemical Name: 2-(1-(tert-Butyl)-5-(furan-2-yl)-1H-pyrazol-3-yl)-5-chloro-1H-benzo[d]imidazole
Purity: >98% (HPLC)
Novel potent and selective P2Y6R antagonist (IC50 = 5.914 nM), effectively ameliorating DSS-induced ulcerative colitis in mice through inhibiting the activation of NLRP3 inflammasome in colon tissues
Reference:
https://pubs.acs.org/doi/10.1021/acs.jmedchem.3c00210
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