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CAS: N/A
Chemical Name: 1-Cyclopropyl-3-(3-oxo-3H-phenoxazin-2-yl)urea
For Lab R&D Uses Only
Purity: >98% (HPLC)
First-in-class potent antitubercular agent, disrupting mycobacterial envelope integrity by inhibiting Malonyl CoA-acyl carrier protein transacylase (encoded by FabD gene), an unexploited target in the essential mycolic acid biosynthesis pathway
Reference:
https://pubs.acs.org/doi/10.1021/acs.jmedchem.5c02148
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