Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 905579-51-3
Chemical Name: Pevonedistat; QCR-143; [(1S,2S,4R)-4-[4-[[(1S)-2,3-Dihydro-1H-inden-1-yl]amino]pyrrolo[2,3-d]pyrimidin-7-yl]-2-hydroxycyclopentyl]methyl sulfamate
Cat No: GLXC-90203
For R&D Uses Only
Purity: > 98% (HPLC)
Storage: Refrigerator (4 °C)
Novel inhibitor of CRL E3s, inhibiting the formation of Kras(G12D)-induced lung tumors through a similar mechanism involving inactivation of NF-κB and mTOR and accumulation of tumor suppressor substrates
References:
https://pubmed.ncbi.nlm.nih.gov/?term=MLN4924&sort=date
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