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Andrographolide analogue 3A.1

 

CAS: N/A

 

Chemical Name: 19-tert-Butyldiphenylsilyl-8,7-epoxy andrographolide; (4S,E)-3-(2-((1S,2S,5R,6R,8aR)-5-(((tert-Butyldiphenylsilyl)oxy)methyl)-6-hydroxy-5,8a-dimethyloctahydro-1H-spiro[naphthalene-2,2'-oxiran]-1-yl)ethylidene)-4-hydroxydihydrofuran-2(3H)-one

 

 
GLXC-25134For Lab R&D Uses Only
        Cat No: GLXC-25134

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel anticancer agent against metastatic Castration resistance and neuroendocrine variant prostate cancers (mCRPC/NEPC), exhibiting synergistic anticancer effect in combination with standard therapy docetaxel and cabazitaxel in mCRPC/NEPC, upregulating Heat Shock proteins and downregulating MAT2A-mediated cell migration and invasion

 

Ref: https://jpet.aspetjournals.org/content/early/2021/12/23/jpet.121.000898

 

Analytical data click for PDF file

 

 

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