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CAS: 2276680-91-0
Chemical Name: N-[(1R,2R)-2-{3-[5-(Difluoromethyl)-1,3,4-oxadiazol-2-yl]-5-oxo-5H,6H,7H-pyrrolo[3,4-b]pyridin-6-yl}cyclohexyl]-2,2,3,3,3-pentafluoropropanamide
Purity: >98% (HPLC)
Novel, potent, highly selective HDAC6 inhibitor, showing brain penetration in an oral dose and blocked HDAC6-dependent tubulin deacetylation at Lys40, exhibiting superior selectivity over other HDACs compared with the known HDAC6 inhibitors in the enzyme and cellular assays
Ref: https://www.nature.com/articles/s41598-021-94923-w
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