Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 138-86-3
Chemical Name: Limonene; Dipentene; Cyclohexene; 1-Methyl-4-prop-1-en-2-ylcyclohexene
For Lab R&D Uses Only
Purity: >98% (HPLC)
Natural suppressor of interleukin (IL)-1 β-induced NF-κB, JNK and p38 activation and the expression of inflammatory (iNOS) and catabolic (MMP-1 and MMP-13) genes, significantly elevating collagen synthesis, alkaline phosphatase activity, osteocalcin synthesis, and mineralization in osteoblastic cells, increasing the activation of anti-catabolic genes (TIMP-1) and ERK1/2 relative to IL-1β-treated cells in a cellular model of osteoarthritis
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