Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 118344-71-1
Chemical Name: Methylbenzoprim; NSC-382035; 5-[4-[Benzyl(methyl)amino]-3-nitrophenyl]-6-ethylpyrimidine-2,4-diamine
Purity: >98% (HPLC)
First-in-class multifunctional thymidylate synthase (TYMS) inhibitor, exhibiting enhanced antitumor activity as compared to current fluoropyrimidines and antifolates without inducing TYMS overexpression, extending survival in both pancreatic xenograft tumor models and hTS/Ink4a/Arf null genetically engineered mouse tumor model
Reference:
https://insight.jci.org/articles/view/158798/pdf
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