Glixx Laboratories Inc

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Glixx Laboratorie

 

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TYMS inhibitor 19-S

 

CAS: 118344-71-1

 

Chemical Name: Methylbenzoprim; NSC-382035; 5-[4-[Benzyl(methyl)amino]-3-nitrophenyl]-6-ethylpyrimidine-2,4-diamine

 

 
GLXC-27318For Lab R&D Uses Only
        Cat No: GLXC-27318

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

First-in-class multifunctional thymidylate synthase (TYMS) inhibitor, exhibiting enhanced antitumor activity as compared to current fluoropyrimidines and antifolates without inducing TYMS overexpression, extending survival in both pancreatic xenograft tumor models and hTS/Ink4a/Arf null genetically engineered mouse tumor model

 

Reference:

https://insight.jci.org/articles/view/158798/pdf

 

Analytical data click for PDF file

 

 

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