Glixx Laboratories Inc
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Glixx Laboratorie
CAS: N/A
Chemical Name: 1-Amino-N-(pyridin-2-ylmethyl)benzo[4,5]imidazo[1,2-a]pyrazine-3-carboxamide dihydrochloride
Purity: >98% (HPLC)
Novel highly potent A2AAR antagonist (Ki = 0.08 nM), significantly inhibiting the growth of triple-negative breast cancer by reversing immunosuppressive tumor microenvironment in the xenograft mouse model without severe toxicity at the testing dose
Ref: https://pubs.acs.org/doi/10.1021/acs.jmedchem.2c00101
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