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JNJ-61803534

 

CAS: 1917306-14-9

 

Chemical Name: (R)-5-(2,3-Dichloro-4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-N-(2-hydroxy-2-methylpropyl)-4-(2-methylpyrrolidine-1-carbonyl)thiazole-2-carboxamide

 

 
GLXC-24209For Lab R&D Uses Only
        Cat No: GLXC-24209

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel potent RORγt inverse agonist, selectively inhibiting RORγt-driven transcription versus closely-related family members, RORα and RORβ, also inhibiting IL-17A production in human CD4+ T cells under Th17 differentiation conditions, but not inhibiting IFNγ production under Th1 differentiation conditions, and having neither impact on in vitro differentiation of regulatory T cells (Treg), nor on the suppressive activity of natural Tregs

 

Ref: https://www.nature.com/articles/s41598-021-90497-9


Analytical data click for PDF file

 

 

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