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PARP1/BRD4 inhibitor III-7

 

CAS: 2758117-74-5

 

Chemical Name: 2-((6-(3,5-Dimethylisoxazol-4-yl)-1-methyl-2-oxo-4-phenyl-1,4-dihydroquinazolin-3(2H)-yl)methyl)-1H-benzo[d]imidazole-4-carboxamide

 

 
GLXC-25413For Lab R&D Uses Only
        Cat No: GLXC-25413

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel highly selective dual PARP1/BRD4 inhibitor (PARP1 IC50=49nM; BRD4 IC50=202nM), repressing the expression and activity of PARP1 and BRD4 to synergistically inhibit the malignant growth of pancreatic cancer cells in vitro and in vivo

 

Ref: https://www.sciencedirect.com/science/article/abs/pii/S0223523422000186

 

Analytical data click for PDF file

 

 

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