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Glixx Laboratorie
CAS: 2304621-06-3
Chemical Name: IMT1; Inhibitor of mitochondrial transcription 1; (3S)-1-((2R)-2-((4-(2-Chloro-4-fluorophenyl)-2-oxo-4a,8a-dihydro-2H-chromen-7-yl)oxy)propanoyl)piperidine-3-carboxylic acid
Purity: >98% (HPLC)
First-in-class human mitochondrial RNA polymerase (POLRMT) inhibitor
Reference:
https://www.nature.com/articles/s41419-024-06444-9#Sec27
https://pubs.acs.org/doi/10.1021/acs.jmedchem.3c00058
https://www.nature.com/articles/s41586-020-03048-z
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