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Coibamide A

 

CAS: 1029227-48-2

 

Chemical Name: N-{(2S)-2-[(N,N-Dimethyl-L-valyl)oxy]-3-methylbutanoyl}-N,O-dimethyl-L-seryl-N-[(3S,6S,9S,12S,15S,18S,21S,22R)-15-[(2S)-2-butanyl]-9-isobutyl-6-(4-methoxybenzyl)-18-(methoxymethyl)-3,4,10,12,16,19,22- ;heptamethyl-2,5,8,11,14,17,20-heptaoxo-1-oxa-4,7,10,13,16,19-hexaazacyclodocosan-21-yl]-N,N2-dimethyl-L-leucinamide

 

 
GLXC-22668For Lab R&D Uses Only
        Cat No: GLXC-22668

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Natural lariat depsipeptide, inhibiting VEGFA/VEGFR2 expression and suppressing tumor growth in glioblastoma xenografts, targeting Sec61 to prevent biogenesis of secretory and membrane proteins

 

References:

1) https://pubs.acs.org/doi/10.1021/acschembio.0c00325

2) https://pubs.acs.org/doi/10.1021/acs.jmedchem.8b01141

3) https://www.mdpi.com/1660-3397/16/3/77

 

Analytical data click for PDF file

 

 

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