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CAS: 195256-59-8
Chemical Name: [(2R,3S,4S,5R,6S)-6-[[6-[2-(1-Carbamimidoyl-2,5-dihydropyrrol-3-yl)ethylcarbamoyl]-12-hydroxy-7-[(2R,3S)-2-[(2-methoxy-3-sulfooxypropanoyl)amino]-3-methylpentanoyl]-3-oxo-2-oxa-4,7-diazatricyclo[6.3.1.01,5]dodecan-10-yl]oxy]-5-hexanoyloxy-3,4-dihydroxyoxan-2-yl]methyl hexanoate
Purity: >98% (HPLC)
Natural potent trypsin inhibitor, inhibiting human trypsin-2 and -3 with IC50 values of 4.7 and 11.5 nM, respectively, while trypsin-1 being inhibited with an IC50 of 104 nM
References:
1) https://pubs.acs.org/doi/10.1021/acschembio.1c00611
2) https://pubs.rsc.org/en/content/articlelanding/2009/CS/b915448p
3) https://onlinelibrary.wiley.com/doi/10.1002/anie.200803655
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