Glixx Laboratories Inc

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Glixx Laboratorie

 

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CDK9 PROTAC 955

 

CAS: N/A

 

Chemical Name: PL-SNS-032 conjugate 955; (E)-N-(5-(((5-(tert-Butyl)oxazol-2-yl)methyl)thio)thiazol-2-yl)-1-(2-(4-(2-(2,6-dimethoxy-4-(3-oxo-3-(6-oxo-3,6-dihydropyridin-1(2H)-yl)prop-1-en-1-yl)phenoxy)ethyl)piperazin-1-yl)-2-oxoethyl)piperidine-4-carboxamide

 

 
GLXC-26995For Lab R&D Uses Only
        Cat No: GLXC-26995

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel CDK9 degrader, potently degrading CDK9 in a ubiquitin-proteasome-dependent manner and being much more potent than SNS-032 against various tumor cells in vitro, recruiting KEAP1 via covalent binding

 

Reference:

https://www.cell.com/cell-chemical-biology/fulltext/S2451-9456(23)00027-2

 

Analytical data click for PDF file

 

 

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