Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 2406276-78-4
Chemical Name: OM1700; N-((1S,3r)-3-(5-(5-Ethoxypyridin-2-yl)-4-(2-fluorophenyl)-4H-1,2,4-triazol-3-yl)cyclobutyl)picolinamide
Purity: >98% (HPLC)
Novel potent and selective tankyrase inhibitor, showing a favorable ADME profile, including improved Caco-2 permeability and oral bioavailability in mice, and exhibiting antiproliferative efficacy in the colon cancer cell line COLO 320DM in vitro
References:
1) https://pubs.acs.org/doi/10.1021/acs.jmedchem.0c00208
2) https://jeccr.biomedcentral.com/articles/10.1186/s13046-021-01950-6
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