Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 2396465-33-9
Chemical Name: (1R,3R)-3-((3-Bromo-1-(4-(5-methyl-1,3,4-thiadiazol-2-yl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl)amino)-N,1-dimethylcyclopentane-1-carboxamide
Purity: >98% (HPLC)
Novel cell-potent GCN2 inhibitor with excellent selectivity against its closely related Integrated Stress Response (ISR) family members heme-regulated inhibitor kinase (HRI), protein kinase R (PKR), and (PKR)-like endoplasmic reticulum kinase (PERK), as well as good kinome-wide selectivity and favorable PK
Ref: https://pubs.acs.org/doi/10.1021/acs.jmedchem.2c00736
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