Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 1449592-94-2
Chemical Name: 2-(8-Fluoro-2-methylimidazo[1,2-a]pyridin-6-yl)-7-(4-methylpiperazin-1-yl)-4H-pyrido[1,2-a]pyrimidin-4-one
Purity: >98% (HPLC)
Novel specific splicing enhancer, targeting RNA for a specific splicing correction, recognizing the interface between U1 snRNP and the SMN2 E7 5ʹ SS, promoting the U1-C zinc finger RNA duplex binding activity
References:
1) https://www.nature.com/articles/s41589-019-0384-5
2) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684323/
3) https://www.pnas.org/content/115/20/E4604
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