Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 5707-55-1
Chemical Name: 3,4-Dihydroxyphenylacetaldehyde; Protocatechuatealdehyde
Cat No: GLXC-03720
Purity: > 98% (HPLC)
Storage: Refrigerator (4 °C)
Toxic dopamine metabolite in Parkinson's Disease, being far more potent than dopamine both in oligomerizing and forming quinone-protein adducts with ("quinonizing") αSynuclein, triggering αSynuclein oligomerization leading to synapse physiology impairment; Irreversible Inhibitor of tyrosine hydroxylase
References:
1) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6728988/
2) http://jpet.aspetjournals.org/content/early/2019/11/19/jpet.119.262246.long
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