Glixx Laboratories Inc
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Glixx Laboratorie
CAS: N/A
Chemical Name: N-[4-[(1,1-Dioxido-4-thiomorpholinyl)methyl]phenyl]-4-methyl-1,2,3-thiadiazole-5-carboxamide
Purity: >98% (HPLC)
Novel anti-virulence agent, inhibiting the mycobacterial ESX-1 secretion system, impairing intracellular mycobacterial growth and blocking necrotic cell death of human macrophages, acting as a direct EthR inhibitor inducing dysregulation of ethA, subsequently leading to augmented ethionamide activity
Reference:
https://www.cell.com/cell-chemical-biology/pdf/S2451-9456(23)00436-1.pdf
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