Glixx Laboratories Inc
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Glixx Laboratorie
CAS: N/A
Chemical Name: (3S,12S,15S,18S,22S,23aS)-12-((S)-2-Acetamido-3-(4-hydroxyphenyl)propanamido)-22-acrylamido-18-((R)-1-hydroxyethyl)-15-isobutyl-1,9,13,16,19-pentaoxodocosahydro-1H-pyrrolo[2,1-c][1,4,7,10,16]pentaazacyclohenicosine-3-carboxamide
Purity: >98% (HPLC)
Novel covalent TRF2TRFH domain binder, preventing recruitment of RTEL1 and SLX4 to TRF2 in cells, inducing telomeric replication stress and reducing cancer cell viability
Reference:
https://www.cell.com/cell-chemical-biology/fulltext/S2451-9456(23)00423-3
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