Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 2231745-56-3
Chemical Name: 3-((1-Amino-2,7-naphthyridin-4-yl)ethynyl)-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide
Purity: >98% (HPLC)
Novel potent and selective HUNK inhibitor, diminishing Rubicon S92 phosphorylation, cell survival, and tumorigenesis in human HER2+ breast cancer, resulting in gene expression changes equivalent to HUNK shRNA, also inhibiting other kinases including ABL1, BRAF, FLT3, and RET
Reference:
https://www.cell.com/cell-chemical-biology/fulltext/S2451-9456(24)00037-0
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