Glixx Laboratories Inc

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HSL119

 

CAS: 2231745-56-3

 

Chemical Name: 3-((1-Amino-2,7-naphthyridin-4-yl)ethynyl)-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide

 

 
GLXC-28208For Lab R&D Uses Only
        Cat No: GLXC-28208

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel potent and selective HUNK inhibitor, diminishing Rubicon S92 phosphorylation, cell survival, and tumorigenesis in human HER2+ breast cancer, resulting in gene expression changes equivalent to HUNK shRNA, also inhibiting other kinases including ABL1, BRAF, FLT3, and RET

 

Reference:

https://www.cell.com/cell-chemical-biology/fulltext/S2451-9456(24)00037-0

 

Analytical data click for PDF file

 

 

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