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Glixx Laboratorie
CAS: 3029515-97-4
Chemical Name: 4-(Trifluoromethyl)benzyl 4-(6-(2,6-dihydroxy-3-nitrobenzoyl)pyrazolo[1,5-a]pyrimidin-2-yl)benzoate
Purity: >98% (HPLC)
Novel and selective ALKBH5 inhibitor for the treatment of AML, increasing the abundance of m6A modifications in AML cells, reducing the mRNA stability of TACC3, inhibiting cell cycle progression, and significantly suppressing tumor growth in the MV4-11 xenograft mouse model
Reference:
https://pubs.acs.org/doi/10.1021/acs.jmedchem.3c01374
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