Glixx Laboratories Inc

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DDO-2728

 

CAS: 3029515-97-4

 

Chemical Name: 4-(Trifluoromethyl)benzyl 4-(6-(2,6-dihydroxy-3-nitrobenzoyl)pyrazolo[1,5-a]pyrimidin-2-yl)benzoate

 

 
GLXC-27972For Lab R&D Uses Only
        Cat No: GLXC-27972

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel and selective ALKBH5 inhibitor for the treatment of AML, increasing the abundance of m6A modifications in AML cells, reducing the mRNA stability of TACC3, inhibiting cell cycle progression, and significantly suppressing tumor growth in the MV4-11 xenograft mouse model

 

Reference:

https://pubs.acs.org/doi/10.1021/acs.jmedchem.3c01374

 

Analytical data click for PDF file

 

 

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