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Glixx Laboratorie
CAS: 2728291-29-8
Chemical Name: N-(1H-Benzo[d]imidazol-6-yl)-2-(4-bromophenoxy)acetamide
Purity: >98% (HPLC)
Novel potent P2Y14R antagonist (IC50 = 0.6 nM), demonstrating satisfactory inhibitory activity on the inflammatory response of monosodium urate (MSU)-induced acute gouty arthritis, decreasing inflammatory factor release and cell pyroptosis through the NOD-like receptor family pyrin domain-containing 3 (NLRP3)/gasdermin D (GSDMD) signaling pathway
Reference:
https://pubs.acs.org/doi/10.1021/acs.jmedchem.4c00555
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