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P2Y14R Antagonist I-17

 

CAS: 2728291-29-8

 

Chemical Name: N-(1H-Benzo[d]imidazol-6-yl)-2-(4-bromophenoxy)acetamide

 

 
GLXC-28675For Lab R&D Uses Only
        Cat No: GLXC-28675

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel potent P2Y14R antagonist (IC50 = 0.6 nM), demonstrating satisfactory inhibitory activity on the inflammatory response of monosodium urate (MSU)-induced acute gouty arthritis, decreasing inflammatory factor release and cell pyroptosis through the NOD-like receptor family pyrin domain-containing 3 (NLRP3)/gasdermin D (GSDMD) signaling pathway

 

Reference:

https://pubs.acs.org/doi/10.1021/acs.jmedchem.4c00555

 

Analytical data click for PDF file

 

 

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