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CAS: N/A
Chemical Name: Z21090; 4-(6-Chloro-4-ethoxy-1H-pyrazolo[4,3-c]pyridin-1-yl)butanoic acid
Purity: >98% (HPLC)
Novel potent PDE4 inhibitor (IC50 = 37.4 nM) for the treatment of alcohol use disorder (AUD) and alcoholic liver diseases by decreasing alcohol intake and improving acute alcohol-induced sedation and motor impairment, displaying the potential to alleviate alcoholic liver injury and attenuate inflammation in the NIAAA mice model
Reference:
https://pubs.acs.org/doi/10.1021/acs.jmedchem.3c02087
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