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ZNL0325

 

CAS: N/A

 

Chemical Name: 1-(3-((4-Amino-1-(tert-butyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl)oxy)azetidin-1-yl)prop-2-en-1-one

 

 
GLXC-28198For Lab R&D Uses Only
        Cat No: GLXC-28198

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel covalent kinase probe, exhibiting a flipped binding mode where the C3 position is oriented toward the ribose binding pocket, forming a covalent bond with multiple kinases that possess a cysteine at the αD-1 position including BTK, EGFR, BLK, and JAK3

 

Reference:

https://pubs.acs.org/doi/10.1021/acs.jmedchem.3c01891

 

Analytical data click for PDF file

 

 

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