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PTP1B Inhibitor MY17

 

CAS: N/A

 

Chemical Name: (Z)-N-(5-((4-Cyanobenzyl)thio)-1,3,4-thiadiazol-2-yl)-4-((2,4-dioxothiazolidin-5-ylidene)methyl)benzamide

 

 
GLXC-28525For Lab R&D Uses Only
        Cat No: GLXC-28525

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel potent, reversible, noncompetitive inhibitor of PTP1B (IC50 = 0.41 ± 0.05 μM), alleviating palmitic acid (PA)-induced insulin resistance by upregulating the expression of phosphorylated insulin receptor substrate and protein kinase B, reducing the fasting blood glucose level and improve glucose tolerance and dyslipidemia in mice suffering from diabetes mellitus (DM)

 

Reference:

https://pubs.acs.org/doi/10.1021/acs.jmedchem.4c00676


Analytical data click for PDF file

 

 

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