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PVD-06

 

CAS: N/A

 

Chemical Name: (2S,4R)-1-((S)-2-(6-(2-(4-(7-(1,1-Dioxido-4-oxo-1,2,5-thiadiazolidin-2-yl)-8-fluoro-6-hydroxynaphthalen-2-yl)-1H-pyrazol-1-yl)acetamido)hexanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide

 

 
GLXC-27965For Lab R&D Uses Only
        Cat No: GLXC-27965

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel subtype-selective and efficient PTPN2 degrader (PTPN2/PTP1B selective index > 60-fold), inducing PTPN2 degradation in a ubiquitination- and proteasome-dependent manner

 

Reference:

https://pubs.acs.org/doi/10.1021/acs.jmedchem.3c01348

 

Analytical data click for PDF file

 

 

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