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CAS: N/A
Chemical Name: (2S,4R)-1-((S)-2-(5-(4-(((6-(4-(4-((4,4-Dimethylpiperidin-1-yl)methyl)-2,5-difluorophenyl)-2-oxo-1,4,9-triazaspiro[5.5]undecan-9-yl)pyrimidin-4-yl)amino)methyl)phenyl)pent-4-ynamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-((R)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide
Purity: >98% (HPLC)
Novel potent METTL3-targeted PROTAC degrader, selectively reducing the METTL3 and METTL14 complex
Reference:
https://www.cell.com/cell-chemical-biology/abstract/S2451-9456(23)00439-7
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