Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 1561172-42-6
Chemical Name: 4-(11H-Indolo[3,2-c]quinolin-6-yl)aniline
For Lab R&D Uses Only
Purity: >98% (HPLC)
Novel potent Skp1 inhibitor with KD ~0.054 μM, interacting with F-box proteins, disrupting SCF E3 ligase(s) functioning, recapitulating previously reported effects of Skp1-reduced activity, and eliciting cell death by a p53-dependent mechanism
Reference:
https://www.cell.com/iscience/fulltext/S2589-0042(22)00863-X
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