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Glixx Laboratorie
CAS: N/A
Chemical Name: 2,2'-((((((4,4'-(Propane-1,3-diylbis(azanediyl))bis(4-oxobutanoyl))bis(azanediyl))bis(4,1-phenylenesulfonyl))bis(azanediyl))bis(naphthalene-4,1-diyl))bis(((4-methoxyphenyl)sulfonyl)azanediyl))diacetic acid
Purity: >98% (HPLC)
Novel unique bivalent KEAP1 inhibitor, engaging cellular KEAP1 dimer to directly release sequestered NRF2 protein, leading to an instant NRF2 activation, promoting the nuclear translocation of NRF2, directly suppressing proinflammatory cytokine transcription
Reference:
https://www.cell.com/cell-chemical-biology/fulltext/S2451-9456(23)00435-X
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