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RANKL inhibitor 4aa

 

CAS: N/A

 

Chemical Name: (R)-3-Methyl-2-(phenylselanyl)-N-(pyridin-3-yl)-3-(2,2,2-trifluoroethoxy)butanamide

 

 
GLXC-28467For Lab R&D Uses Only
        Cat No: GLXC-28467

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel RANKL inhibitor, potently inhibiting RANKL-induced osteoclastogenesis, F-actin ring generation, bone resorption, and osteoclast-specific gene expression in vitro, significantly ameliorating bone loss in an ovariectomized (OVX) mice model, regulating the inhibition of osteoclast differentiation and stimulation of osteoblast

 

Reference:

https://pubs.acs.org/doi/10.1021/acs.jmedchem.4c00438

 

Analytical data click for PDF file

 

 

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