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MAT2A Inhibitor AZ9567

 

CAS: N/A

 

Chemical Name: AZ’9567; 3-Cyclopropyl-4-(4-(difluoromethoxy)phenyl)-6-(2-methyl-2H-indazol-5-yl)-1,4-dihydro-5H-pyrazolo[4,3-b]pyridin-5-one

 

 
GLXC-28358For Lab R&D Uses Only
        Cat No: GLXC-28358

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel in vivo MAT2a tool inhibitor, showing a selective antiproliferative effect on methylthioadenosine phosphorylase (MTAP) KO cells, both in vitro and in vivo, providing further evidence to support the utility of MAT2a inhibitors as potential anticancer therapies for MTAP-deficient tumors

 

Reference:

https://pubs.acs.org/doi/10.1021/acs.jmedchem.3c01860

 

Analytical data click for PDF file

 

 

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