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MLKL inhibitor P28

 

CAS: N/A

 

Chemical Name: Methyl (E)-3-(3-(3-(3-hydroxyphenyl)prop-2-yn-1-yl)-1,7-dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)acrylate

 

 
GLXC-27764For Lab R&D Uses Only
        Cat No: GLXC-27764

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel mixed-lineage kinase domain-like (MLKL) inhibitor, demonstrating potent necroptosis inhibition and antifibrotic effects, inhibiting immune cell death, reducing the expression of adhesion molecules and the level of activation of hepatic stellate cells and the expression of hepatic fibrosis markers induced by necroptosis stimulation

 

Reference:

https://pubs.acs.org/doi/10.1021/acsptsci.3c00131

 

Analytical data click for PDF file

 

 

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