Glixx Laboratories Inc
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Glixx Laboratorie
CAS: N/A
Chemical Name: (E)-(2-(4-(3,5-Dimethoxystyryl)phenoxy)acetoxy)(hydroxy)platinum(IV) dichloride diammonia complex
Purity: >98% (HPLC)
Novel STAT3 inhibitor, regulating the tumor microenvironment, exerting remarkable antiproliferative activity against the triple-negative BC cells, suppressing the expression of phosphorylated STAT3 and STAT3-related cyclooxygenase-2 and IL-6, and activating caspase-3 and cleaving poly ADP-ribose polymerase, preventing the repair of DNA lesions and inducing apoptosis
Reference:
https://pubs.acs.org/doi/10.1021/acs.jmedchem.3c00836
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