Glixx Laboratories Inc

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Glixx Laboratorie

 

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FHD-286

 

CAS: 2671128-05-3

 

Chemical Name: N-[(2S)-1-[[4-[6-[(2S,6R)-2,6-Dimethylmorpholin-4-yl]pyridin-2-yl]-1,3-thiazol-2-yl]amino]-3-methoxy-1-oxopropan-2-yl]-1-methylsulfonylpyrrole-3-carboxamide

 

 
GLXC-28000For Lab R&D Uses Only
        Cat No: GLXC-28000

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel orally bioavailable, allosteric inhibitor of transcription activator BRG1 and BRM, leading to the inhibition of the SWI/SNF chromatin remodeling complex, disrupting chromatin remodeling and gene expression, and resulting in the downregulation of oncogenic pathways and the inhibition of tumor cell proliferation

 

References:

https://ashpublications.org/blood/article-abstract/141/19/2372/493945/DNA-polymerase-protects-leukemia-cells-from?redirectedFrom=fulltext

https://ashpublications.org/bloodadvances/article/7/17/5000/495643/Interaction-between-myelodysplasia-related-gene


 

Analytical data click for PDF file

 

 

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