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CAS: N/A
Chemical Name: N-((3-Bromo-4,5-dihydroisoxazol-5-yl)methyl)-4-chloro-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxamide
Purity: >98% (HPLC)
Novel covalent inhibitor of T cell activation and proliferation, engaging cysteines within functionally diverse protein sites including ribosomal protein S5 (RPS5), inosine monophosphate dehydrogenase 2 (IMPDH2), and heat shock protein 60 (HSP60)
Reference:
https://pubs.acs.org/doi/abs/10.1021/acschembio.4c00025
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