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CAS: N/A
Chemical Name: (R)-4-((7-Cyclopentyl-8-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropyrimido[5,4-d]pyrimidin-2-yl)amino)-3-methoxy-N-(3-(4-((2-(3-((2-methoxy-4-(methylsulfonyl)phenyl)amino)prop-1-yn-1-yl)-1-(2,2,2-trifluoroethyl)-1H-indol-4-yl)amino)piperidin-1-yl)-3-oxopropyl)benzamide
For Lab R&D Uses Only
Purity: >98% (HPLC)
Novel potent and selective TP53 mutant cell death inducer, targeting sp53Y220C-PLK1 (EC50: 25 nM)
Reference:
https://www.biorxiv.org/content/10.1101/2024.07.27.605429v1.full.pdf
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