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CAS: 1163729-79-0
Chemical Name: N2,N4-Bis(2,4-dimethylquinolin-6-yl)-6-methylpyrimidine-2,4-diamine
For Lab R&D Uses Only
Purity: >98% (HPLC)
Novel DOT1L inhibitor (IC50 = 1.5 μM), competitively occupying the binding site of S-adenosylmethionine, selectively inhibits MLL-rearranged cell proliferation with an IC50 value of 37.1 μM
Reference:
https://pubs.acs.org/doi/10.1021/acs.jcim.5b00738
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