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CAS: 2922675-91-8
Chemical Name: 2-Cyclopentyl-4-(7-((10-(((S)-1-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-10-oxodecyl)oxy)quinazolin-4-yl)benzoic acid
Purity: >98% (HPLC)
Novel potent and selective CaMKK2 degrader (IC50 = 9 nM; 92% degradation; DC50 = 100 nM)
Reference:
https://pubs.acs.org/doi/10.1021/acs.jmedchem.3c01137
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