Glixx Laboratories Inc

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SBL-PX1-206

 

CAS: N/A

 

Chemical Name: 2-((3S,6S,9S,12S,15S,Z)-3-((3S,6S,9S,12S,15S,Z)-6-((1H-Indol-3-yl)methyl)-12-(3-amino-3-oxopropyl)-3-(6-((S)-2,5-diaminopentanamido)hexanamido)-9-(3-guanidinopropyl)-4,7,10,13-tetraoxo-11H-5,8,11,14-tetraaza-1(4,1)-triazolacyclononadecaphane-15-carboxamido)-15-(((S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl)carbamoyl)-6-benzyl-9-isopropyl-4,7,10,13-tetraoxo-11H-5,8,11,14-tetraaza-1(4,1)-triazolacyclononadecaphane-12-yl)acetic acid

 

 
GLXC-27742For Lab R&D Uses Only
        Cat No: GLXC-27742

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel bidirectional inhibitor of Panx1 channel function, inhibiting ATP release from endothelial cells, thereby efficiently reducing THP-1 monocyte adhesion to a TNF-α-activated endothelial monolayer

 

Reference:

https://pubs.acs.org/doi/10.1021/acs.jmedchem.3c01116

 

Analytical data click for PDF file

 

 

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