For Lab R&D Uses Only

Purity:               >98% (HPLC)

Product Description:

Novel survivin inhibitor by targeting ILF3/NF110 for cancer therapy, remarkably inhibiting nonsmall cell lung cancer cells A549 with an IC50 value of 9 nM and solid tumor cell proliferation with more than 700-fold selectivity against human normal cells, significantly inhibiting survivin expression and colony formation and induced ROS production, apoptosis, cell cycle arrest, DNA damage, and autophagy

Reference:

https://pubs.acs.org/doi/10.1021/acs.jmedchem.3c01551

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