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CAS: N/A
Chemical Name: Cyclo(Ac-Cha-Cys(1)-Arg-Leu-Cha-Arg-Arg-Cha-Cys(2)-Arg-C(O)NH2 Ac-Cha-Cys(2)-Arg-Leu-Cha-Arg-Arg-Cha-Cys(1)-Arg-C(O)NH2)
Purity: >98% (HPLC)
Novel ROS blocker, targeting nephrotoxic AKI and colistin-induced mitochondrial dysfunction, selectively binding to abnormal mitochondria, preserving the cristae structure impaired by mitochondria-damaging agents, protecting cristae, reducing ROS production, and enhancing adenosine triphosphate (ATP) generation
Reference:
https://pubs.acs.org/doi/10.1021/acs.jmedchem.3c01578
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