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CAS: N/A
Chemical Name: 10-Bromo-N-((3S,4S)-4-(3,4-difluorophenyl)piperidin-3-yl)-5,6-dihydropyrazolo[1,5-d]thieno[3,2-f][1,4]oxazepine-2-carboxamide
Purity: >98% (HPLC)
Novel Akt/ROCK inhibitor, displaying strong antiproliferative effects and excellent differentiation inducing activity against Neuro2a cells, resulting in the arrest of G0/G1 cell cycles, a significant decrease in N-myc protein level, and an increase in differentiation markers, effectively suppressing xenograft tumor growth
Reference:
https://pubs.acs.org/doi/10.1021/acs.jmedchem.3c00829
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