Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 2585648-55-9
Chemical Name: 15-[(5-Fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]-9-propan-2-yl-5-(trifluoromethyl)-4,9,12,14,16-pentazatetracyclo[9.6.1.02,7.014,18]octadeca-1(17),2,4,6,11(18),12,15-heptaen-10-one
Purity: >98% (HPLC)
Novel highly potent embryonic ectoderm development (EED) inhibitor (IC50 = 0.2 nM), inhibiting the KARPAS422 cell growth with an IC50 value of 1.2 nM and leading to complete and persistent tumor regression in the KARPAS422 xenograft model with no signs of toxicity
Reference:
https://pubs.acs.org/doi/10.1021/acs.jmedchem.1c01059
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