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CAS: N/A
Chemical Name: 5-(1-(2,6-Dimethoxy-4-(2-methyl-1-oxo-1,2-dihydroisoquinolin-4-yl)benzyl)piperidin-4-yl)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
Purity: >98% (HPLC)
Novel potent and selective BRD9 degrader (DC50 value of 1.02 ± 0.52 nM) for treating acute myelocytic leukemia, exhibiting superior oral activity, showing no degradations of BRD4 or BRD7
Reference:
https://www.sciencedirect.com/science/article/abs/pii/S0223523423008395
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