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CAS: 292873-23-5
Chemical Name: 3-Cyclohexyl-5-((E)-4-hydroxy-3-iodo-5-nitrobenzylidene)-2-(phenylimino)thiazolidin-4-one
Purity: >98% (HPLC)
Novel BCL-2 inhibitor, targeting the BH4 domain, inducing cell killing in a BCL-2-dependent manner and triggered apoptosis via the mitochondria-mediated pathway, disrupting the BCL-2/c-Myc interaction and consequently suppressing the transcriptional activity of c-Myc, inhibiting tumor growth in vivo in a BCL‑2‑dependent manner
Reference:
https://www.nature.com/articles/s41401-022-00936-0
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