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µOR Agonist/σ1R Antagonist 4x

 

CAS: 3009018-61-2

 

Chemical Name: N-(2-(4-Phenylpiperidin-1-yl)butyl)-N-(pyridin-2-yl)propionamide

 

 
GLXC-27990For Lab R&D Uses Only
        Cat No: GLXC-27990

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel dual μOR agonist/σ1R antagonist, displaying picomolar μOR agonism activity (EC50: 0.6 ± 0.2 nM) and good σ1R inhibitory activity (Ki: 363.7 ± 5.6 nM) with excellent selectivity, exhibiting robust analgesic effects in various pain models, with significantly reduced side effects

 

Reference:

https://pubs.acs.org/doi/10.1021/acs.jmedchem.3c01637

 

Analytical data click for PDF file

 

 

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