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Rogocekib

 

CAS: 2144751-78-8

 

Chemical Name: CTX-712; 2-[(1R)-1-Fluoroethyl]-5-[[6-(4-methoxypyrrolo[2,1-f][1,2,4]triazin-5-yl)-2-methylimidazo[4,5-b]pyridin-1-yl]methyl]-1,3,4-oxadiazole

 

 
GLXC-28646For Lab R&D Uses Only
        Cat No: GLXC-28646

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel orally available and highly potent CLK inhibitor, showing anti-leukemic activities both in vitro and in vivo, potently suppressing phosphorylation of major serine/arginine-rich (SR) domain-containing splicing factors (SFs)

 

References:

https://ashpublications.org/blood/article/140/Supplement%201/489/490010/CTX-712-a-Novel-Splicing-Modulator-Targeting

https://ashpublications.org/blood/article/140/Supplement%201/6211/487205/A-First-in-Human-Phase-I-Study-of-CTX-712-in

https://www.sciencedirect.com/science/article/abs/pii/S0968089622003145

 

Analytical data click for PDF file

 

 

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