Glixx Laboratories Inc

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Glixx Laboratorie

 

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NP3-562

 

CAS: 2409825-32-5

 

Chemical Name: (R)-2-(2-Chloro-5-(2-hydroxypropan-2-yl)-8-oxothieno[2',3':4,5]pyrrolo[1,2-d][1,2,4]triazin-7(8H)-yl)-N-(1-methylpiperidin-3-yl)acetamide

 

 
GLXC-28115For Lab R&D Uses Only
        Cat No: GLXC-28115

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel potent, orally bioavailable NLRP3 inhibitor, binding to the NLRP3 NACHT domain revealing a unique binding mode, demonstrating excellent potency in human whole blood and full inhibition of IL-1β release in a mouse acute peritonitis model at 30 mg/kg po dose

 

Reference:

https://pubs.acs.org/doi/10.1021/acs.jmedchem.3c02098


Analytical data click for PDF file

 

 

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