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PARP1/2/7 inhibitor Cpd36

 

CAS: 2435657-10-4

 

Chemical Name: Sodium 1-(4-fluoro-3-(3-oxo-4-(pentan-3-yl)piperazine-1-carbonyl)benzyl)-2,4-dioxo-1,4-dihydro-2H-quinazolin-3-ide

 

 
GLXC-27828For Lab R&D Uses Only
        Cat No: GLXC-27828

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel PARP1/2/7 inhibitor (PARP-1: IC50 = 0.94 nM; PARP-2: IC50 = 0.87 nM; PARP-7: IC50 = 0.21 nM) with high selectivity over other PARP isoforms, significantly repressing the tumor growth in both breast cancer and prostate cancer xenograft model

 

Reference:

https://pubs.acs.org/doi/10.1021/acs.jmedchem.3c01152

 

Analytical data click for PDF file

 

 

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