Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 2435657-10-4
Chemical Name: Sodium 1-(4-fluoro-3-(3-oxo-4-(pentan-3-yl)piperazine-1-carbonyl)benzyl)-2,4-dioxo-1,4-dihydro-2H-quinazolin-3-ide
Purity: >98% (HPLC)
Novel PARP1/2/7 inhibitor (PARP-1: IC50 = 0.94 nM; PARP-2: IC50 = 0.87 nM; PARP-7: IC50 = 0.21 nM) with high selectivity over other PARP isoforms, significantly repressing the tumor growth in both breast cancer and prostate cancer xenograft model
Reference:
https://pubs.acs.org/doi/10.1021/acs.jmedchem.3c01152
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